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HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies In the autosomal dominant form

SKU: 7889204942

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HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies In the autosomal dominant formHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear

Store: nyherosfund.org · Domain: nyherosfund.org

Description

In the autosomal dominant form

Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins

a coiled-coil domain

Defects in this gene are a cause of Pitt-Hopkins syndrome

HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies In the autosomal dominant formHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear

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