CDKN3 Polyclonal Antibody, 100ul[BT-AP07567] Proteases Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include GTPase activator activity

14-dihydro-prostaglandin E2

and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4)

Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress

CDKN3 Polyclonal Antibody, 100ul[BT-AP07567] Proteases Gene Ontology (GO) annotations relatedThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this