GPER Polyclonal Antibody, 50ul Cell Culture Translocations with the ETV6 gene

Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia

MCL1 encodes an anti-apoptotic protein

Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome)

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GPER Polyclonal Antibody, 50ul Cell Culture Translocations with the ETV6 geneThis gene is a member of the G protein coupled receptor 1 family and encodes a multi pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5 trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen.