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PMVK Polyclonal Antibody, 100ul Peptide Modification The protein encoded by this

SKU: 80392673088

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PMVK Polyclonal Antibody, 100ul Peptide Modification The protein encoded by thisThis gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5 phosphate into mevalonate 5 diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3 hydroxy 3 methylglutaryl coenzyme A reductase, the rate limiting enzyme of cholesterol biosynthesis.

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Description

The protein encoded by this gene belongs to the Fbxs class and| as a transcriptional target of the tumor protein p53| is thought to be involved in degradation of specific proteins in response to p53 induction

as well as the EDG family of proteins

Pseudogenes of this gene have been identified on chromosome 5

In human| ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter| and both genes are paternally expressed

PMVK Polyclonal Antibody, 100ul Peptide Modification The protein encoded by thisThis gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5 phosphate into mevalonate 5 diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3 hydroxy 3 methylglutaryl coenzyme A reductase, the rate limiting enzyme of cholesterol biosynthesis.

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