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SGCD Polyclonal Antibody, 20ul Insect Expression May play an important role

SKU: 80430729375

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SGCD Polyclonal Antibody, 20ul Insect Expression May play an important roleThe protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin glycoprotein complex (DGC). DGC forms a link between the F actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb girdle muscular dystrophy and dilated cardiomyopathy.

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Description

May play an important role in lens epithelial to fiber cell terminal differentiation

This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER

Multiple alternatively spliced transcript variants have been described

Their diverse functions include regulating neurotransmitter release| heart rate| insulin secretion| neuronal excitability| epithelial electrolyte transport| smooth muscle contraction| and cell volume

SGCD Polyclonal Antibody, 20ul Insect Expression May play an important roleThe protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin glycoprotein complex (DGC). DGC forms a link between the F actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb girdle muscular dystrophy and dilated cardiomyopathy.

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