CDR1 Polyclonal Antibody, 50ul Biochemical Reagents Defects in CD3E cause immunodeficiency

Defects in CD3E cause immunodeficiency

MRC2 encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains

This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons

Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling

CDR1 Polyclonal Antibody, 50ul Biochemical Reagents Defects in CD3E cause immunodeficiencyAutoantibodies directed against the protein encoded by this intronless gene have been found in some patients with paraneoplastic cerebellar degeneration. The encoded protein contains several hexapeptide repeats.