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MYOC Polyclonal Antibody, 50ul Custom DNA Oligos Members of this protein family

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MYOC Polyclonal Antibody, 50ul Custom DNA Oligos Members of this protein familyMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile onset

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Description

Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking

Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein

and may play a role in lymphocyte homing to secondary lymphoid organs

which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells

MYOC Polyclonal Antibody, 50ul Custom DNA Oligos Members of this protein familyMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile onset

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