Caspase-1 Polyclonal Antibody, 100ul[BT-AP01192] Custom Peptide Synthesis Inhibits differentiation of CD34+ cell

Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro)

in particular during tumorigenesis

and chemokine b receptor-like 1 (CMKBRL1) with high affinity

Alternatively spliced transcript variants encoding different isoforms have been identified

Caspase-1 Polyclonal Antibody, 100ul[BT-AP01192] Custom Peptide Synthesis Inhibits differentiation of CD34+ cellCASP1 (caspase 1) encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically