Aven Polyclonal Antibody, 50ul Bio-Reaction Tube Proteolytic cleavage is important for

Proteolytic cleavage is important for targeting of the proteins to the NPC

They may participate in fatty acyl and cholesterol ester metabolism

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Two pseudogenes of this gene have been identified on chromosomes 10 and 4

Aven Polyclonal Antibody, 50ul Bio-Reaction Tube Proteolytic cleavage is important forAVEN, a cell death regulator, is an important signal inducer in acute leuke mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf 1 mediated apoptosis by interfering with Apaf 1's ability to self associate. Bcl 2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be