ALK-1 Polyclonal Antibody, 50ul[BT-AP00373] Roller Bottles The mature factor is activated

The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway)

The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine

May function as a transcriptional regulator

making them unavailable for display on antigen-presenting cells

ALK-1 Polyclonal Antibody, 50ul[BT-AP00373] Roller Bottles The mature factor is activatedACVRL1 (activin A receptor like type 1) encodes a type I cell surface receptor for the TGF beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine threonine kinase subdomains, a glycine and serine rich region (called the GS domain) preceding the kinase domain, and a short C terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or