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RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator with the most highly conserved

SKU: 82920058729

4.1
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RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator with the most highly conservedRFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have

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Description

with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters

The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure

The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13

The protein has been implicated in the development of Alzheimer disease

RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator with the most highly conservedRFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have

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