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Integrin beta 1(Phospho Thr789) Polyclonal Antibody, 100ul Vector Construction A germline mutation of VHL

SKU: 82953495138

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Integrin beta 1(Phospho Thr789) Polyclonal Antibody, 100ul Vector Construction A germline mutation of VHLIntegrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants

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Description

A germline mutation of VHL is the basis of familial inheritance of VHL syndrome

Forms a ternary complex with NF2/merlin and GRB2

not easy to break

Several different transcript variants encoding different isoforms have been found for this gene

Integrin beta 1(Phospho Thr789) Polyclonal Antibody, 100ul Vector Construction A germline mutation of VHLIntegrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants

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