Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 100ul Variant Libraries The cytoplasmic Beta- and γ-actin

The cytoplasmic Beta- and γ-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility

This protein has been implicated in the pathogenesis of Alzheimer's disease

Most of the encoded protein is located in the nucleus but some is also present in mitochondria

and is most closely related to mitogen-activated protein kinases (MAP kinases)

Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 100ul Variant Libraries The cytoplasmic Beta- and γ-actinThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.