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Per2 Polyclonal Antibody, 20ul Drug Development and Evaluation Mutations in this gene result

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Per2 Polyclonal Antibody, 20ul Drug Development and Evaluation Mutations in this gene resultPER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK ARNTL heterodimers but then represses this upregulation in a feedback loop using PER CRY heterodimers to

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Description

Mutations in this gene result in autosomal recessive spastic paraplegia

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and it may play a role in the pathophysiology of obesity

It is an orphan receptor

Per2 Polyclonal Antibody, 20ul Drug Development and Evaluation Mutations in this gene resultPER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK ARNTL heterodimers but then represses this upregulation in a feedback loop using PER CRY heterodimers to

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