RPGF6 Polyclonal Antibody, 100ul Cell fragmentation and collection involved in the regulation of

involved in the regulation of neuronal spine density (By similarity)

Mutations in this gene are associated with septooptic dysplasia

This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17

|tissue specificity:Expressed in hematopoietic cells and also in colon and testis

RPGF6 Polyclonal Antibody, 100ul Cell fragmentation and collection involved in the regulation ofGuanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M Ras GTPases. Does not interact with cAMP.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 cyclic nucleotide binding domain.,Contains 1 N terminal Ras GEF domain.,Contains 1 PDZ (DHR) domain.,Contains 1 Ras associating domain.,Contains 1 Ras GEF domain.,subcellular location: Upon binding to M Ras, it translocates to the plasma membrane.,subunit: Interacts with the