Phospho-Caspase-9 (T125) Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein specifically regulates

The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways

and is essential for IL18 mediated signal transduction

angiogenesis and T-cell function

a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif

Phospho-Caspase-9 (T125) Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein specifically regulatesCASP9 encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a