JMJD2B Polyclonal Antibody, 50ul Sealing Film Vora (1981) [PubMed 6451249] determined

Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4

PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family

Transcriptional regulator that acts as repressor or activator

Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia

JMJD2B Polyclonal Antibody, 50ul Sealing Film Vora (1981) [PubMed 6451249] determinedHistone demethylase that specifically demethylates 'Lys 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys 4', H3 'Lys 27', H3 'Lys 36' nor H4 'Lys 20'. Only able to demethylate trimethylated H3 'Lys 9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.