TPR Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection CREBBP is ubiquitously expressed and

CREBBP is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors

including the protein encoded by this gene

It localizes primarily within subnuclear foci associated with the nuclear matrix

and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake

TPR Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection CREBBP is ubiquitously expressed andThis gene encodes a large coiled coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.