Grap Polyclonal Antibody, 50ul Buffers & Solutions Contains 1 EGF-like domain

Contains 1 EGF-like domain

Alternate splicing results in both coding and non-coding transcript variants

Flap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis

|subcellular location:Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation

Grap Polyclonal Antibody, 50ul Buffers & Solutions Contains 1 EGF-like domainGRAP encodes a member of the GRB2 Sem5 Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through