ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome This gene is located in

This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias

Expression of this gene may be downregulated in pancreatic cancer

which are important regulators of hematopoiesis and cardiogenesis in mammals

The encoded protein is related to a plant protein that participates in ultraviolet B light-sensing during root morphogenesis

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome This gene is located inERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation