Rat Metabotropic Glutamate Receptor 4, GRM4 ELISA Kit, 96T Gene Editing Plays a role in the

Plays a role in the generation of resolution phase interaction products (resolvins) during both sterile and infectious inflammation (PubMed: 12391014)

Allelic variants of this gene exist that confer susceptibility to diabetes mellitus

but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited

Component of the transcription regulatory histone acetylation (HAT) complex SAGA

Rat Metabotropic Glutamate Receptor 4, GRM4 ELISA Kit, 96T Gene Editing Plays a role in theG protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide binding proteins (G proteins) and modulates the activity of down stream effectors. Signaling inhibits adenylate cyclase activity.