PAK Alpha Polyclonal Antibody, 50ul[BT-AP06895] Drug Development and Evaluation |PTM:Phosphorylated when associated with the

|PTM:Phosphorylated when associated with the catalytic subunit

This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions

including a leucine zipper sequence

and both proteins act together in the regulation of late endocytic traffic

PAK Alpha Polyclonal Antibody, 50ul[BT-AP06895] Drug Development and Evaluation |PTM:Phosphorylated when associated with thePAK1 encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.