GPNMB Polyclonal Antibody, 50ul Pipette Filler Defects in protein kinase C

Defects in protein kinase C gamma have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14)

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This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel

GPNMB Polyclonal Antibody, 50ul Pipette Filler Defects in protein kinase CThe protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for