Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes Directly involved in heterochromatin formation

Directly involved in heterochromatin formation by maintaining overall chromatin structure and| in particular| that of constitutive heterochromatin by stabilizing histone methylation

The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes

including defects in septation

These family members contain multiple N-terminal leucine-rich repeats| in addition to a C-terminal calponin homology domain| a type of domain that mediates interactions with actin filaments

Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes Directly involved in heterochromatin formationAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone