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DnaJB4 Polyclonal Antibody, 20ul Oligo Pool It plays an important role

SKU: 85400472102

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DnaJB4 Polyclonal Antibody, 20ul Oligo Pool It plays an important roleDnaJ heat shock protein family (Hsp40) member B4encoded by DNAJB4 is a molecular chaperone, tumor suppressor, and member of the heat shock protein 40 family. The encoded protein binds the cell adhesion protein E cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E cadherin and targets it for endoplasmic reticulum associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and

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Description

It plays an important role in the suppression of proliferation-associated genes

Transduces a signal by increasing intracellular calcium ion levels

second only to ABO

Mutations in CHEK2 have been linked with Li-Fraumeni syndrome

DnaJB4 Polyclonal Antibody, 20ul Oligo Pool It plays an important roleDnaJ heat shock protein family (Hsp40) member B4encoded by DNAJB4 is a molecular chaperone, tumor suppressor, and member of the heat shock protein 40 family. The encoded protein binds the cell adhesion protein E cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E cadherin and targets it for endoplasmic reticulum associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and

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