FILA2 Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes a protein involved in nucleotide

a protein involved in nucleotide excision repair

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons

The leukocyte immunoglobulin like receptor A2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response

The proprotein is further processed into numerous smaller functional peptides

FILA2 Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes a protein involved in nucleotideThe filaggrin like protein encoded by this gene is upregulated by calcium proteolyzed by calpain 1 and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact in addition to providing a physical barrier C terminal fragments of this protein display antimicrobial activity