Mcl-1 Polyclonal Antibody, 100ul[BT-AP05274] Gene Synthesis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been identified in this gene

Phosphorylation promotes association of TFEB with 14-3-3 family proteins and retention in the cytosol

and is required for the biological activities of IL3

Several alternative

Mcl-1 Polyclonal Antibody, 100ul[BT-AP05274] Gene Synthesis Alternatively spliced transcript variants encodingMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.