KRT82 Polyclonal Antibody, 20ul Cryogenic Vials Several human genetic disorders are

Several human genetic disorders are caused by aberrations in human homeobox genes

Mutations in this gene cause autosomal dominant severe congenital neutropenia

Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage

This protein is also found to interact with BRCA1 and BRCA2

KRT82 Polyclonal Antibody, 20ul Cryogenic Vials Several human genetic disorders areThe protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less related subfamily includes