Ref-1 Polyclonal Antibody, 20ul[BT-AP07734] Glassware Sets and it is implicated in

and it is implicated in interstrand-cross-link repair

a positive regulator of programmed cell death

Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID)

This protein has been shown to form a stable heterodimer with the family member RAD51C

Ref-1 Polyclonal Antibody, 20ul[BT-AP07734] Glassware Sets and it is implicated inApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.