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Raf-1 Polyclonal Antibody, 50ul[BT-AP13532] Liquid Handling &Storage FANCM and FANCN (also called

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Raf-1 Polyclonal Antibody, 50ul[BT-AP13532] Liquid Handling &Storage FANCM and FANCN (also calledThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

FANCM and FANCN (also called PALB2)

The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling

The protein binds to RNA via two KH domains and also colocalizes with MEX3A| Dcp1A decapping factor and Argonaute proteins within P (processing) bodies

Additional splice variants have been described but sequences for the complete transcripts have not been determined

Raf-1 Polyclonal Antibody, 50ul[BT-AP13532] Liquid Handling &Storage FANCM and FANCN (also calledThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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