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Paxillin Polyclonal Antibody, 100ul[BT-AP06957] sgRNA Oligos This gene is found in

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Paxillin Polyclonal Antibody, 100ul[BT-AP06957] sgRNA Oligos This gene is found inPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

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Description

This gene is found in the histone microcluster on chromosome 6p21

This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues

Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin

alpha- and beta-globin

Paxillin Polyclonal Antibody, 100ul[BT-AP06957] sgRNA Oligos This gene is found inPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

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