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RPGF4 Polyclonal Antibody, 50ul Mechanical Pipette An important paralog of this

SKU: 87976426694

4.4
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RPGF4 Polyclonal Antibody, 50ul Mechanical Pipette An important paralog of thisThe DEP domain is involved in membrane localization independent from regulation by cAMP.,The N terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2.,Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP dependent, PKA independent exocytosis through interaction with RIMS2.,Contains 1 DEP

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Description

An important paralog of this gene is HLA-DMA

In addition| this protein interacts with BRCA1 and is phosphorylated by ATM| indicating a potential role for this protein in DNA repair

The N-terminal half shares moderate homology with regions of calmodulin and M-calpain

Internalization and recycling of integrin receptors is important in cell adhesion and migration modulation

RPGF4 Polyclonal Antibody, 50ul Mechanical Pipette An important paralog of thisThe DEP domain is involved in membrane localization independent from regulation by cAMP.,The N terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2.,Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP dependent, PKA independent exocytosis through interaction with RIMS2.,Contains 1 DEP

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