Human Tek Tyrosine Kinase, Endothelial, TIE2 ELISA Kit, 96T Contamination Detection & Removal The encoded protein also suppresses

The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1

cytokine secretion and the inflammatory response (By similarity)

Alternatively spliced transcript variants encoding different isoforms have been noted for PPP1R14A

This protein functions as a monomer

Human Tek Tyrosine Kinase, Endothelial, TIE2 ELISA Kit, 96T Contamination Detection & Removal The encoded protein also suppressesProduces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. [Isoform eNOS13C]: Lacks eNOS activity, dominant negative form that may down regulate eNOS activity by forming heterodimers with isoform 1.