Rat Muscarinic Acetylcholine Receptor M2, CHRM2 ELISA Kit, 96T Recombinant Ab Production This gene encodes a 59

This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP)

Experimental confirmation may be lacking for some isoforms

This gene contains several nonsense codons compared to other family members that render the transcript a candidate for nonsense-mediated mRNA decay (NMD)

A pseudogene of AURKB is located on chromosome 8

Rat Muscarinic Acetylcholine Receptor M2, CHRM2 ELISA Kit, 96T Recombinant Ab Production This gene encodes a 59The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium Channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity).