Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the founding

NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins

This protein plays a role in regulating cell migration

Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain

this subunit

Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the foundingThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a