TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been identified

More than a dozen pseudogenes of this gene have been identified

but they differ significantly over the 3' untranslated regions

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids

TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variantsKLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2 type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.