MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter subcellular location:Shuttles between nucleus and

subcellular location:Shuttles between nucleus and cytoplasm

The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor

This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family

Most isoforms share a common C-terminal domain

MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter subcellular location:Shuttles between nucleus andThe protein encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.