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AR Monoclonal Antibody, 100ul[BT-MCA0179] Metabolic enzymes tool compounds Promotes anchorage-independent growth of immortalized

SKU: 90385769529

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AR Monoclonal Antibody, 100ul[BT-MCA0179] Metabolic enzymes tool compounds Promotes anchorage-independent growth of immortalizedThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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Description

Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion

The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions

and also with yeast Vps4 and mouse Skd1 proteins

This gene encodes a regulatory subunit of the SMG1 complex

AR Monoclonal Antibody, 100ul[BT-MCA0179] Metabolic enzymes tool compounds Promotes anchorage-independent growth of immortalizedThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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