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OCLN Polyclonal Antibody, 50ul Peptide Synthesis TERF2IP encodes a protein that

SKU: 90622561529

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OCLN Polyclonal Antibody, 50ul Peptide Synthesis TERF2IP encodes a protein thatThis gene encodes an integral membrane protein that is required for cytokine induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band like calcification with simplified gyration and polymicrogyria (BLC PMG), an autosomal recessive neurologic disorder that is also known as pseudo TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene

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Description

TERF2IP encodes a protein that is part of a complex involved in telomere length regulation

cell division and cell death

A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis

The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate

OCLN Polyclonal Antibody, 50ul Peptide Synthesis TERF2IP encodes a protein thatThis gene encodes an integral membrane protein that is required for cytokine induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band like calcification with simplified gyration and polymicrogyria (BLC PMG), an autosomal recessive neurologic disorder that is also known as pseudo TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene

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