LPL Monoclonal Antibody, 50ul Electronic Pipette Allelic variations in this gene

Allelic variations in this gene are associated with heparin cofactor II deficiency

a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53

Four transcript variants encoding the same protein have been identified for this gene

TFEB is activated in response to nutrient deprivation

LPL Monoclonal Antibody, 50ul Electronic Pipette Allelic variations in this geneLPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand bridging factor for receptor mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.