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KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification This intronless gene HSPA1A(heat shock

SKU: 91064631987

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KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification This intronless gene HSPA1A(heat shockKANK2 encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.

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Description

This intronless gene HSPA1A(heat shock protein family A(Hsp70) member 1A) encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family

The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins

It also suppresses p53-induced growth arrest

The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation

KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification This intronless gene HSPA1A(heat shockKANK2 encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.

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