HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody, 100ul Mammalian Expression A chromosomal translocation involving this

A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia

Because of its chromosomal localization and ability to form heterodimers with other polypeptides

Y genotype

Alternative splicing of this gene results in two transcript variants which encode the same protein

HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody, 100ul Mammalian Expression A chromosomal translocation involving thisThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin