Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction MIM 607362) and contributes to

MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al

it is required for maximal ATPase activity of BRG1

Could play an important role in mediating local tissue responses to inflammatory conditions

More than a dozen pseudogenes of this gene have been identified

Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction MIM 607362) and contributes toThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.