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MSH2 Polyclonal Antibody, 50ul Electrophoresis & Labeling Grp78 and following heat shock

SKU: 93427309597

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MSH2 Polyclonal Antibody, 50ul Electrophoresis & Labeling Grp78 and following heat shockMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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Description

Grp78 and following heat shock

Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome

neural tube defects

which may be essential for the oncogenic effects of LMP1

MSH2 Polyclonal Antibody, 50ul Electrophoresis & Labeling Grp78 and following heat shockMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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