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Tcl1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube The CHD family of proteins

SKU: 93464846539

4.5
USD162.00 USD201.00

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Tcl1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube The CHD family of proteinsOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T cell antigen receptor (TCR) alpha (MIM 186880) or TCR beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998

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Description

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains

KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK)

MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase| MAPK kinase/MEK| which in turn activates MAPK

it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration

Tcl1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube The CHD family of proteinsOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T cell antigen receptor (TCR) alpha (MIM 186880) or TCR beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998

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