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DBLOH Polyclonal Antibody, 20ul Cellular Function Assays The palladin

SKU: 93684277352

4.5
PLN97.20 PLN143.20

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DBLOH Polyclonal Antibody, 20ul Cellular Function Assays The palladinThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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Description

The palladin

thus differing from the other known gene family members

The encoded protein is a key regulator of cardiac diastolic function

Required for nuclear receptor-mediated transactivation

DBLOH Polyclonal Antibody, 20ul Cellular Function Assays The palladinThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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