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UNC5B Polyclonal Antibody, 100ul PCR Series this gene is established as

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UNC5B Polyclonal Antibody, 100ul PCR Series this gene is established asThis gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin 1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro and anti apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

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Description

this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas

suggesting that the receptor couples with G-protein G(q) and G(i)

Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain

development and immune responses

UNC5B Polyclonal Antibody, 100ul PCR Series this gene is established asThis gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin 1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro and anti apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

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