Shc Polyclonal Antibody, 100ul[BT-AP08290] Purification cortactin is degraded in a

cortactin is degraded in a caspase-dependent manner

Hard and wear-resistant PP

The encoded protein homodimerizes and functions as an outwardly rectifying channel

is activated during development by Wnt/Fz signaling to control cell polarity and movement

Shc Polyclonal Antibody, 100ul[BT-AP08290] Purification cortactin is degraded in aSHC1 encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike the