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ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene are
ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene are
ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene are
ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene are

ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene are

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ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene areZinc finger protein 420 encoded by ZNF420 is a KRAB type zinc finger protein that negatively regulates p53 mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.

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Description

Mutations in this gene are associated with Pendred syndrome

Designed for maximum stability

the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi

preferentially methionine

ZNF420 Polyclonal Antibody, 50ul Reservoirs Mutations in this gene areZinc finger protein 420 encoded by ZNF420 is a KRAB type zinc finger protein that negatively regulates p53 mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.

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