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Gas8 Polyclonal Antibody, 100ul Cell Screening and Imaging TSN encodes a DNA-binding protein

SKU: 95677764712

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SEK141.00 SEK183.00

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Gas8 Polyclonal Antibody, 100ul Cell Screening and Imaging TSN encodes a DNA-binding proteinGAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16 or f3, that is transcribed in the opposite orientation. GAS8 is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene.

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Description

TSN encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations

Defects in this gene appear to be a cause of various types of leukemia or lymphoma

a protein involved in fatty acid oxidation

May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes

Gas8 Polyclonal Antibody, 100ul Cell Screening and Imaging TSN encodes a DNA-binding proteinGAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16 or f3, that is transcribed in the opposite orientation. GAS8 is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene.

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